Collaborative center to support knowledge transfer to low-resource partners AMIA, the U.S.-based association for informatics professionals, has launched a non-profit, wholly owned subsidiary organization called the Global Health Informatics Partnership (GHIP) to serve as an international center for collaborative initiatives on health informatics. With generous operational support from AMIA, GHIP (say “gee-hip”), aims to...
Read more »
Clinical trials for promising new drug candidate are planned LA JOLLA, CA – August 30, 2010 –– An international team led by scientists from The Scripps Research Institute, the Swiss Tropical Institute, the Genomics Institute of the Novartis Research Foundation and the Novartis Institute for Tropical Diseases has discovered a promising new drug candidate...
Read more »
Half of the malaria medication sold In Africa could be ineffective or even harmful. Researchers from Lund and the UK have now developed a technique that could resolve the situation Counterfeiting of drugs is a huge industry with an annual turnover of more than SEK 500 billion. In Africa the situation is extremely serious....
Read more »
It now appears that the malaria mosquito needs more than one family of odor sensors to sniff out its human prey. That is the implication of new research into the mosquito’s sense of smell published in the Aug. 31 issue of the online, open-access journal Public Library of Science Biology.
Read more »
![Reconstitution of CD4 T Cells in Bronchoalveolar Lavage Fluid after Initiation of Highly Active Antiretroviral Therapy [Vaccines and Antiviral Agents]](http://img.zemanta.com/zemified_e.png?x-id=dfc4eddc-8c5f-4eff-bba1-f34e466bd54f)
The massive depletion of gastrointestinal-tract CD4 T cells is a hallmark of the acute phase of HIV infection. In contrast, the depletion of the lower-respiratory-tract mucosal CD4 T cells as measured in bronchoalveolar lavage (BAL) fluid is more moderate and similar to the depletion of CD4 T cells observed in peripheral blood (PB).
Read more »
Monkeypox has increased 20-fold in Democractic Republic of Congo since 1980 In the winter of 1979, the world celebrated the end of smallpox, a highly contagious and often fatal viral infection estimated to have caused between 300 and 500 million deaths during the 20th century. The virus was eradicated through an aggressive worldwide vaccination...
Read more »
![Macaques Vaccinated with Simian Immunodeficiency Virus SIVmac239{Delta}nef Delay Acquisition and Control Replication after Repeated Low-Dose Heterologous SIV Challenge [Vaccines and Antiviral Agents]](http://img.zemanta.com/zemified_e.png?x-id=9e26758d-320b-4479-8eb2-fcea69a6ae99)
An effective human immunodeficiency virus (HIV) vaccine will likely need to reduce mucosal transmission and, if infection occurs, control virus replication. To determine whether our best simian immunodeficiency virus (SIV) vaccine can achieve these lofty goals, we vaccinated eight Indian rhesus macaques with SIVmac239nef and challenged them intrarectally (i.r.) with repeated low doses of...
Read more »
![Alpha/Beta Interferon (IFN-{alpha}/{beta})-Independent Induction of IFN-{lambda}1 (Interleukin-29) in Response to Hantaan Virus Infection [Cellular Response to Infection]](http://img.zemanta.com/zemified_e.png?x-id=1ee1d95e-6c2e-41ac-b96e-02481301c401)
Type III interferons (IFN- and interleukin-28 and -29 ) are recently recognized cytokines with innate antiviral effects similar to those of type I IFNs (IFN-/β). Like IFN-/β, IFN–expression can be induced by viruses, and it is believed that type I and III IFNs are regulated in the same manner. Hantaviruses are weak IFN-/β inducers...
Read more »