WASHINGTON, April 18—Correctly and quickly diagnosing malaria is essential for effective and life-saving treatment. But rapid detection, particularly in remote areas, is not always possible because current methods are time-consuming and require precise instrumentation and highly skilled microscopic analysis. Now, a promising new optical imaging system, described in a paper published today in the Optical Society’s (OSA) open-access journalBiomedical Optics Express, may make the diagnosis of this deadly disease much easier, faster, and more accurate. Read More
The contribution of Plasmodium chabaudi to our understanding of malaria
Trends in Parasitology, Volume 28, Issue 2, February 2012, Pages 73-82
Robin Stephens, Richard L Culleton, Tracey J Lamb.
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Challenges and prospects for malaria elimination in the Southern Africa region
Acta Tropica, Volume 121, Issue 3, March 2012, Pages 207-211
William J Moss, Douglas E Norris, Sungano Mharakurwa, Alan Scott, Modest Mulenga, Peter R Mason, James Chipeta, Philip E Thuma, for the Southern Africa ICEMR Team.
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Management of uncomplicated malaria in febrile under five-year-old children by community health workers in Madagascar: reliability of malaria rapid diagnostic tests
Background:
Early diagnosis, as well as prompt and effective treatment of uncomplicated malaria, are essential components of the anti-malaria strategy in Madagascar to prevent severe malaria, reduce mortality and limit malaria transmission. The purpose of this study was to assess the performance of the malaria rapid diagnostic tests (RDTs) used by community health workers (CHWs) by comparing RDT results with two reference methods (microscopy and Polymerase Chain Reaction, PCR). Read More
Differences in selective pressure on dhps and dhfr drug resistant mutations in western Kenya
Background:
Understanding the origin and spread of mutations associated with drug resistance, especially in the context of combination therapy, will help guide strategies to halt and prevent the emergence of resistance. Unfortunately, studies have assessed these complex processes when resistance is already highly prevalent. Even further, information on the evolutionary dynamics leading to multidrug-resistant parasites is scattered and limited to areas with low or seasonal malaria transmission. Read More
Antibodies to malaria vaccine candidates are associated with chloroquine or sulphadoxine/pyrimethamine treatment efficacy in children in an endemic area of Burkina Faso
Background:
Patient immune status is thought to affect the efficacy of anti-malarial chemotherapy. This is a subject of some importance, since evidence of immunity-related interactions may influence our use of chemotherapy in populations with drug resistance, as well as assessment of the value of suboptimal vaccines. The study aim was to investigate relationship between antibodies and anti-malarial drug treatment outcomes. Read More
Low coverage of intermittent preventive treatment for malaria in pregnancy in Nigeria: demand-side influences
Background:
Nigeria instituted intermittent preventive treatment for malaria (IPTp) using sulphadoxine-pyrimethamine (SP) for pregnant women in 2001, but coverage remains low. This study examined the influence of demand side factors on IPTp coverage. Read More
Do patients adhere to over-the-counter artemisinin combination therapy for malaria? Evidence from an intervention study in Uganda
Background:
Increasing affordability of artemisinin combination therapy (ACT) in the African retail sector could be critical to expanding access to effective malaria treatment, but must be balanced by efforts to protect the efficacy of these drugs. Previous research estimates ACT adherence rates among public sector patients, but adherence among retail sector purchasers could differ substantially. This study aimed to estimate adherence rates to subsidized, over-the-counter ACT in rural Uganda. Read More
Prevalence of malaria infection in Butajira area, south-central Ethiopia
Background:
In 2005, the Ethiopian government launched a massive expansion of the malaria prevention and control programme. The programme was aimed mainly at the reduction of malaria in populations living below 2,000 m above sea level. Global warming has been implicated in the increase in the prevalence of malaria in the highlands. However, there is still a paucity of information on the occurrence of malaria at higher altitudes. The objective of this study was to estimate malaria prevalence in highland areas of south-central Ethiopia, designated as the Butajira area. Read More
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Biodiversity of Malaria in the World :: Amazon This is the English language version of the French work - BiodiversitA du paludisme dans le monde- published by John Libbey in 2004. At the |
Artemisinin and artemisinin plus curcumin liposomal formulations: Enhanced antimalarial efficacy against Plasmodium berghei-infected mice
European Journal of Pharmaceutics and Biopharmaceutics, Volume 80, Issue 3, April 2012, Pages 528-534
Benedetta Isacchi, Maria Camilla Bergonzi, Margherita Grazioso, Chiara Righeschi, Alessia Pietretti, Carlo Severini, Anna Rita Bilia.
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Combination drug treatment can cut malaria by 30 percent
Malaria infections among infants can be cut by up to 30 per cent when antimalarial drugs are given intermittently over a 12 month period, a three-year clinical trial in Papua New Guinea has shown. Read More
Introducing birth control in mosquitoes
Grant to UC Riverside’s Alexander Raikhel can greatly help control population of disease-spreading mosquitoes
RIVERSIDE, Calif. — Female mosquitoes require energy for their egg development, which they acquire from vertebrate blood. But by sucking on blood, they become vectors of numerous disease pathogens of human and domestic animals. If the mechanisms that govern their egg production are better understood, novel approaches to controlling the reproduction and population of mosquitoes can be devised. Read More
Disease Outbreaks- Avian influenza – situation in Indonesia – updateThe Indonesian IHR National Focal Point of the Ministry of Health has notified WHO of a new case of human infection with avian influenza A(H5N1) virus. […]
- Avian influenza – situation in Egypt – updateThe Ministry of Health and Population of Egypt has notified WHO of a new case of human infection with avian influenza A (H5N1) virus. […]
- Avian influenza – situation in Cambodia – updateThe Ministry of Health (MoH) of the Kingdom of Cambodia has announced a confirmed case of human infection with avian influenza A (H5N1) virus. […]
- Lassa fever in NigeriaAt the beginning of 2012, WHO was notified by the Federal Ministry of Health in Nigeria of an outbreak of Lassa fever. As of March 22, 2012, 623 suspected cases, including 70 deaths have been recorded from 19 of the 36 States since the beginning of the year. Laboratory analysis undertaken at the Irrua Specialist Teaching Hospital, Irrua Edo State has confirm […]
- Avian influenza – situation in Egypt – updateThe Ministry of Health and Population of Egypt has notified WHO of two new cases of human infection with avian influenza A (H5N1) virus. […]
- Avian influenza – situation in Indonesia – update
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