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NAIROBI, 27 April 2012 (PLUSNEWS) – East Africa’s Legislative Assembly has passed a regional HIV/AIDS Bill that seeks to protect the rights of people living with HIV and harmonize regional legislation and policy on the prevention and treatment of HIV. |
EAST AFRICA: Regional HIV Bill passed without criminalization clause
UGANDA: Inadequate healthcare and rising HIV prevalence in Karamoja
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MOROTO, 30 April 2012 (PLUSNEWS) – The nomadic Karimojong ethnic group, once regarded as a low-risk HIV population because regional instability in northeastern Uganda and strong adherence to their culture kept them relatively isolated, have not been a priority on the country’s HIV agenda, but recent statistics show prevalence among this community is now 5.8 percent, up from 3.5 percent five years ago. |
Centre for Global Non-Communicable Diseases launched to tackle killer diseases
The Centre for Global Non-Communicable Diseases, a unique initiative that brings together researchers, policy makers, funders and patient advocacy groups worldwide to focus research and expertise on this growing global health challenge, is launched today (25 April) at the London School of Hygiene & Tropical Medicine. Read More
Groundbreaking Nigeria summit results in major commitment to reduce child deaths
Dramatic reduction in child mortality the goal of aggressive push to expand vaccine access in country with second-most child deaths worldwide
Abuja, Nigeria – Nigeria’s top government officials, civil society leaders and leaders of private industry resolved today to join forces to expand vaccine access nationwide, a major step in the fight to reduce child mortality in a country with the world’s second highest number of child deaths. Read More
Vaccine for Neglected Disease Ready for Testing
LISBON – During a meeting in Lisbon, the partners of the BuruliVac research consortium found the project to be running smoothly, and getting closer to a vaccine against Buruli ulcer, a disfiguring and mutilating disease that causes a lot of suffering and now is difficult to treat. Several vaccine candidates work well in mice and are ready for further testing on blood of patients; one is ready for testing in mice. Scientists of the Antwerp Institute of Tropical Medicine play an important role in this endeavour. Read More
UGANDA: Deaf demand inclusion in HIV programmes
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KAMPALA, 2 April 2012 (PLUSNEWS) – Leaders of the deaf community in Uganda say the government’s HIV programmes have failed them because their special needs are not taken into consideration. |
AFRICA: Co-trimoxazole discontinuation linked to increased malaria
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NAIROBI, 11 April 2012 (PLUSNEWS) – Abruptly discontinuing co-trimoxazole – an antibiotic used to prevent opportunistic infections in HIV-positive people – can lead to a higher incidence of malaria and diarrhoea compared with patients who keep on taking the drug, a new study has found. |
KENYA: Better training needed for counsellors of HIV-discordant couples
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NAKURU/NAIROBI, 5 April 2012 (PLUSNEWS) – The Kenyan government has issued guidelines on counselling for HIV-discordant couples, but many counsellors in smaller, rural health centres remain untrained. |
DRC: Kinshasa fashion highlights lack of ARVs
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KINSHASA, 3 April 2012 (PLUSNEWS) – Twelve HIV-positive women held a fashion show in Kinshasa, capital of the Democratic Republic of Congo, on 30 March to highlight the plight of tens of thousands of people with HIV/AIDS, and challenge donors and the authorities to provide adequate treatment. |
Replication of immunodeficiency virus in humans
VIROLOGY Replication of immunodeficiency virus in humans
The acquired immunodeficiency syndrome (AIDS) pandemic is caused by the human immunodeficiency virus (HIV-1), which attacks the immune system and leaves infected individuals susceptible to opportunistic infections. AIDS and HIV-1 are thought to have a relatively short history in humans, with the first infections likely occurring around the turn of the 20th century. Read More
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The Neurology of AIDS :: Amazon Neurological complications of progressive HIV-1 infection remain a common cause of morbidity even during widespread use of antiretroviral th |
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Human Virology :: Amazon Viruses are the smallest of organisms, yet given that they account for at least a third of presentations in the doctors clinic, they must be |
In Vivo Suppression of HIV by Antigen Specific T Cells Derived from Engineered Hematopoietic Stem Cells
by Scott G. Kitchen, Bernard R. Levin, Gregory Bristol, Valerie Rezek, Sohn Kim, Christian Aguilera-Sandoval, Arumugam Balamurugan, Otto O. Yang, Jerome A. Zack
The HIV-specific cytotoxic T lymphocyte (CTL) response is a critical component in controlling viral replication in vivo, but ultimately fails in its ability to eradicate the virus. Our intent in these studies is to develop ways to enhance and restore the HIV-specific CTL response to allow long-term viral suppression or viral clearance. Read More
Treatment with IL-7 Prevents the Decline of Circulating CD4+ T Cells during the Acute Phase of SIV Infection in Rhesus Macaques
by Lia Vassena, Huiyi Miao, Raffaello Cimbro, Mauro S. Malnati, Giulia Cassina, Michael A. Proschan, Vanessa M. Hirsch, Bernard A. Lafont, Michel Morre, Anthony S. Fauci, Paolo Lusso
Although treatment with interleukin-7 (IL-7) was shown to transiently expand the naïve and memory T-cell pools in patients with chronic HIV-1 infection receiving antiretroviral therapy (ART), it is uncertain whether a full immunologic reconstitution can be achieved. Moreover, the effects of IL-7 have never been evaluated during acute HIV-1 (or SIV) infection, a critical phase of the disease in which the most dramatic depletion of CD4+ T cells is believed to occur. Read More









