Tuberculosis transmission to young children in a South African community: modeling household and community infection risks.
Clin Infect Dis. 2010 Aug 15;51(4):401-8
Authors: Wood R, Johnstone-Robertson S, Uys P, Hargrove J, Middelkoop K, Lawn SD, Bekker LG
BACKGROUND: Tuberculosis transmission is determined by contact between infectious and susceptible individuals. A recent study reported a 4% annual risk of child tuberculosis infection in a southern African township. A model was used to explore the interactions between prevalence of adult tuberculosis infection, adult-to-child contacts, and household ventilation, which could result in such a high annual risk of tuberculosis infection. METHODS: Number of residents per household and tuberculosis incidence were derived from a household census and community tuberculosis registers. Read More