AMHERST, Mass. – One of the major problems that has slowed progress toward universal access to life-saving antiretroviral therapy (ART) to treat AIDS in developing nations has been limited availability of laboratories and trained medical staff to conduct blood tests of immune system CD-4 T-cell levels that indicate when to start ART. Read More
Serology and cytokine profiles in patients infected with the newly discovered Bundibugyo ebolavirus.
Virology. 2012 Feb 20;423(2):119-24
Authors: Gupta M, MacNeil A, Reed ZD, Rollin PE, Spiropoulou CF
Abstract
A new species of Ebolavirus, Bundibugyo ebolavirus, was discovered in an outbreak in western Uganda in November 2007. To study the correlation between fatal infection and immune response in Bundibugyo ebolavirus infection, viral antigen, antibodies, and 17 soluble factors important for innate immunity were examined in 44 patient samples. Read More
Background:
Increasing access to health care services is considered central to improving the health of populations. Existing reviews to understand factors affecting access to health care have focused on attributes of patients and their communities that act as ‘barriers’ to access, such as education level, financial and cultural factors. This review addresses the need to learn about provider characteristics that encourage patients to attend their health services. Read More
Background:
In 2004, Ethiopia switched its first-line treatment of uncomplicated Plasmodium falciparum malaria from sulphadoxine-pyrimethamine to a fixed artemisinin-based combination therapy (ACT), artemether-lumefantrine (AL). Patient adherence to AL regimen is a major determining factor to achieve the desired therapeutic outcome. The aim of this study was to measure patient adherence levels to the six-dose AL regimen for the treatment of uncomplicated P. falciparum malaria and to identify its determinant factors in rural areas of the Tigray region, Ethiopia Read More
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Immunology and Immunopathogenesis of Malaria (Current Topics in Microbiology and Immunology) :: Amazon Malaria is still a major global health problem, killing more than 1 million people every year. Almost all of these deaths are caused by Plas |
Response to traditional disease-modifying anti-rheumatic drugs in indigent South Africans with early rheumatoid arthritis.
Clin Rheumatol. 2011 Dec 2;
Authors: Hodkinson B, Musenge E, Ally M, Meyer PW, Anderson R, Tikly M
Abstract
The clinical response to traditional disease-modifying anti-rheumatic drugs (DMARDs) in indigent South Africans with early rheumatoid arthritis was investigated. A cohort of patients with early (≤2 years) RA who were DMARD-naïve at inception were prospectively assessed for response to DMARDs using the Simplified Disease Activity Index (SDAI) over a 12-month period. Read More
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Rheumatoid Arthritis (Oxford Rheumatology Library) :: Amazon Rheumatoid Arthritis is a common rheumatic condition that affects around 1-2% of the population and without adequate therapy results in sign |
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Inflammation and Rheumatic Diseases: The Molecular Basis of Novel Therapies :: Amazon - A sensible synthesis of therapy and practice: This book is a useful guide for students, physicians in continuing education and practitione |
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Arthritis Treatment :: Amazon Breakthroughs in arthritis and auto-immune disease treatment This manuscript explains to both patients and Rheumatologists, in an informativ |
by Benjamin H. Chi, Constantin T. Yiannoutsos, Andrew O. Westfall, Jamie E. Newman, Jialun Zhou, Carina Cesar, Martin W. G. Brinkhof, Albert Mwango, Eric Balestre, Gabriela Carriquiry, Thira Sirisanthana, Henri Mukumbi, Jeffrey N. Martin, Anna Grimsrud, Melanie Bacon, Rodolphe Thiebaut, on behalf of the International Epidemiologic Databases to Evaluate AIDS Collaboration
Background
Although patient attrition is recognized as a threat to the long-term success of antiretroviral therapy programs worldwide, there is no universal definition for classifying patients as lost to follow-up (LTFU). We analyzed data from health facilities across Africa, Asia, and Latin America to empirically determine a standard LTFU definition. Read More
Background:
There is a global consensus towards universal access to human immunodeficiency virus (HIV) services consequent to the increasing availability of antiretroviral therapy. However, to benefit from these services, knowledge of one’s HIV status is critical. Partner notification for HIV is an important component of HIV counselling because it is an effective strategy to prevent secondary transmission, and promote early diagnosis and prompt treatment of HIV patients’ sexual partners. Read More
Background:
East Africa has experienced a rapid expansion in access to antiretroviral therapy (ART) for HIV-infected patients. Regionally representative socio-demographic, laboratory and clinical characteristics of patients accessing ART over time and across sites have not been well described. Read More
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HIV, Third Edition :: Amazon Our understanding of HIV is constantly increasing, and practice standards continue to evolve. What was previously a progressive disease with |
Background:
Delays in the initiation of antiretroviral therapy (ART) in patients with HIV-associated tuberculosis (TB) are associated with increased mortality risk. We examined the timing of ART among patients receiving care provided by non-integrated TB and ART services in Cape Town, South Africa. Read More
Background:
In Tanzania, malaria is the major cause of morbidity and mortality, accounting for about 30% of all hospital admissions and around 15% of all hospital deaths. Severe anaemia and cerebral malaria are the two main causes of death due to malaria in Tanga, Tanzania.
Methods:
This was a prospective observational hospital-based study conducted from October 2004 to September 2005. Consent was sought from study participants or guardians in the wards. Finger prick blood was collected from each individual for thick and thin smears, blood sugar levels and haemoglobin estimations by Haemocue machine after admission. Read More
Background:
Following the development of resistance to anti-malarial mono-therapies, malaria endemic countries in Africa now use artemisinin-based combination therapy (ACT) as recommended first-line treatment for uncomplicated malaria. Read More
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