Accuracy of Five Algorithms to Diagnose Gambiense Human African Trypanosomiasis

by: admin - July 13th, 2011   Filed under: PLOS NTDs Add Comment

by Francesco Checchi, François Chappuis, Unni Karunakara, Gerardo Priotto, Daniel Chandramohan

Background

Algorithms to diagnose gambiense human African trypanosomiasis (HAT, sleeping sickness) are often complex due to the unsatisfactory sensitivity and/or specificity of available tests, and typically include a screening (serological), confirmation (parasitological) and staging component. Read More

Tags: ,

Measuring Fitness of Kenyan Children with Polyparasitic Infections Using the 20-Meter Shuttle Run Test as a Morbidity Metric

by: admin - July 11th, 2011   Filed under: PLOS NTDs Add Comment

by Amaya L. Bustinduy, Charles L. Thomas, Justin J. Fiutem, Isabel M. Parraga, Peter L. Mungai, Eric M. Muchiri, Francis Mutuku, Uriel Kitron, Charles H. King

Background

To date, there has been no standardized approach to the assessment of aerobic fitness among children who harbor parasites. Read More

Tags:

Associations between childhood adversity and depression, substance abuse and HIV and HSV2 incident infections in rural South African youth.

by: admin - October 23rd, 2010   Filed under: PubMed Africa Related Add Comment

Associations between childhood adversity and depression, substance abuse and HIV and HSV2 incident infections in rural South African youth.

Child Abuse Negl. 2010 Oct 11;

Authors: Jewkes RK, Dunkle K, Nduna M, Jama PN, Puren A

OBJECTIVES: To describe prevalence of childhood experiences of adversity in rural South African youth and their associations with health outcomes.

METHODS: We analyzed questionnaires and blood specimens collected during a baseline survey for a cluster randomized controlled trial of a behavioral intervention, and also tested blood HIV and herpes simplex type 2 virus at 12- and 24-month follow up; 1,367 male and 1,415 female volunteers were recruited from 70 rural villages. Read More

Tags: , , , , , , ,

Mycobacterium tuberculosis promotes HIV trans-infection and suppresses major histocompatibility complex class II antigen processing by dendritic cells.

by: admin - October 4th, 2010   Filed under: PubMed Africa Related Add Comment

Mycobacterium tuberculosis promotes HIV trans-infection and suppresses major histocompatibility complex class II antigen processing by dendritic cells.

J Virol. 2010 Sep;84(17):8549-60

Authors: Reuter MA, Pecora ND, Harding CV, Canaday DH, McDonald D

Mycobacterium tuberculosis is a leading killer of HIV-infected individuals worldwide, particularly in sub-Saharan Africa, where it is responsible for up to 50% of HIV-related deaths. Infection by HIV predisposes individuals to M. tuberculosis infection, and coinfection accelerates the progression of both diseases. In contrast to most other opportunistic infections associated with HIV, an increased risk of M. tuberculosis infection occurs during early-stage HIV disease, long before CD4 T cell counts fall below critical levels. Read More

Tags: , , , , , , ,

Antiretroviral drug resistance–implications for HIV/AIDS reduction in sub-saharan Africa and other developing countries.

by: admin - September 30th, 2010   Filed under: PubMed Africa Related Add Comment

Antiretroviral drug resistance–implications for HIV/AIDS reduction in sub-saharan Africa and other developing countries.

Niger J Med. 2010 Jul-Sep;19(3):302-10

Authors: Obiako OR, Murktar HM, Ogoina D

BACKGROUND: The introduction of the highly active antiretroviral therapy in the mid-1990s has significantly reduced morbidities and prolonged the lifespan of people living with HIV However, the emergence of resistance to the antiretroviral drugs is becoming a major cause of treatment failure. While the problem of drug resistance is being tackled in developed countries, not much seem to be done in this regard in developing countries of Africa, Asia and Latin America. This review looked at the regional distribution of HIV groups and subtypes and how this has affected the pattern of antiretroviral resistance. Read More

Tags: , , , , , , ,

How to still kill a resistant parasite

by: admin - September 30th, 2010   Filed under: Featured Add Comment

Scientists from the Institute of Tropical Medicine Antwerp, in collaboration with colleagues from several developing countries, were able to restore a sleeping sickness parasite’s susceptibility to drugs. The parasite causes sleeping sickness in cattle. Because it has become resistant against all currently available drugs, it causes enormous economic losses. Until now, that is. Read More

Tags: , , , , , , ,

The use of insecticide-treated nets for reducing malaria morbidity among children aged 6-59 months, in an area of high malaria transmission in central Cote d’Ivoire

by: admin - September 27th, 2010   Filed under: Parasites & Vectors Add Comment

Background:
Long-lasting insecticidal nets (LLINs) are an important tool for controlling malaria. Much attention has been devoted to determine both the effect of LLINs on the reduction of Plasmodium infection rate and clinically-confirmed malaria cases in sub-Saharan Africa. We carried out epidemiological analyses to investigate whether LLINs impact on Plasmodium prevalence rate and the proportion of clinically-confirmed malaria cases, in five villages in the district of Toumodi, central Cote d’Ivoire. Read More

Tags: , , , , , , ,

Postnatal Depression by HIV Status Among Women in Zimbabwe.

by: admin - September 23rd, 2010   Filed under: PubMed Africa Related Add Comment

Postnatal Depression by HIV Status Among Women in Zimbabwe.

J Womens Health (Larchmt). 2010 Sep 17;

Authors: Chibanda D, Mangezi W, Tshimanga M, Woelk G, Rusakaniko S, Stranix-Chibanda L, Midzi S, Shetty AK

Abstract Background: Postnatal depression (PND) is a serious public health problem in resource-limited countries. Research is limited on PND affecting HIV-infected women in sub-Saharan Africa. Zimbabwe has one of the highest antenatal HIV infection rates in the world. We determined the prevalence and risk factors of PND among women attending urban primary care clinics in Zimbabwe. Read More

Tags: , , , , , , ,

Evaluating the BED Capture Enzyme Immunoassay to Estimate HIV Incidence Among Adults in Three Countries in Sub-Saharan Africa.

by: admin - September 23rd, 2010   Filed under: PubMed Africa Related Add Comment

Evaluating the BED Capture Enzyme Immunoassay to Estimate HIV Incidence Among Adults in Three Countries in Sub-Saharan Africa.

AIDS Res Hum Retroviruses. 2010 Sep 19;

Authors: Kim AA, McDougal JS, Hargrove J, Rehle T, Pillay-Van Wyk V, Puren A, Ekra A, Borget-Alloue MY, Adje-Toure C, Abdullahi AS, Odawo L, Marum L, Parekh BS

Abstract Serological assays for estimating HIV-1 incidence are prone to misclassification, limiting the accuracy of the incidence estimate. Adjustment factors have been developed and recommended for estimating assay-based HIV-1 incidence in cross-sectional settings. We evaluated the performance of the recommended adjustment factors for estimating incidence in national HIV surveys in three countries in sub-Saharan Africa. Read More

Tags: , , , , , , ,

The Effect of Community-Based Support Services on Clinical Efficacy and Health-Related Quality of Life in HIV/AIDS Patients in Resource-Limited Settings in Sub-Saharan Africa.

by: admin - September 6th, 2010   Filed under: PubMed Africa Related Add Comment

The Effect of Community-Based Support Services on Clinical Efficacy and Health-Related Quality of Life in HIV/AIDS Patients in Resource-Limited Settings in Sub-Saharan Africa.

AIDS Patient Care STDS. 2010 Aug 28;

Authors: Kabore I, Bloem J, Etheredge G, Obiero W, Wanless S, Doykos P, Ntsekhe P, Mtshali N, Afrikaner E, Sayed R, Bostwelelo J, Hani A, Moshabesha T, Kalaka A, Mameja J, Zwane N, Shongwe N, Mtshali P, Mohr B, Smuts A, Tiam A

Abstract Antiretroviral therapy (ART) for HIV/AIDS in developing countries has been rapidly scaled up through directed public and private resources. Data on the efficacy of ART in developing countries are limited, as are operational research studies to determine the effect of selected nonmedical supportive care services on health outcomes in patients receiving ART. Read More

Tags: , , , , , , ,

The health education nurse faced with an African HIV-infected patient

by: admin - September 6th, 2010   Filed under: PubMed Africa Related Add Comment

[The health education nurse faced with an African HIV-infected patient]

Soins. 2010 Jul-Aug;(747):31-2

Authors: Tocheport P

The health education nurse faced with an African HIV-infected patient. Disease and death are represented in a completely different manner in Sub-Saharan Africa than in the West. The role of the health education nurse working with African HIV-infected patients requires a socio-ethnological understanding of this cultural context in order to provide a global, personalised and adapted treatment.

PMID: 20799487 [PubMed - in process]

Go to Source

Enhanced by Zemanta
Tags: , , , , , , ,

[Management of stroke in sub-Saharan Africa: Current issues.]

by: admin - September 6th, 2010   Filed under: PubMed Africa Related Add Comment

[Management of stroke in sub-Saharan Africa: Current issues.]

Rev Neurol (Paris). 2010 Aug 26;

Authors: Adoukonou TA, Vallat JM, Joubert J, Macian F, Kabore R, Magy L, Houinato D, Preux PM

In sub-Saharan Africa, stroke is likely to present an increasingly important public health problem with a larger relative share of overall morbidity and mortality. Overall, sub-Saharan Health Care is characterized by a lack of human resources, lack of facilities for special investigations, and especially an absence of specific programs addressing the prevention of cardiovascular conditions. Read More

Tags: , , , , , , ,

Copyright 2002-2012 MednewsAfrica. Creative Commons

WordPress Mobile Themes