AMHERST, Mass. – One of the major problems that has slowed progress toward universal access to life-saving antiretroviral therapy (ART) to treat AIDS in developing nations has been limited availability of laboratories and trained medical staff to conduct blood tests of immune system CD-4 T-cell levels that indicate when to start ART. Read More
by Elizabeth N. Ssemanda, Joshua Levens, Harran Mkocha, Beatriz Munoz, Sheila K. West
Background
Persistent non-participation of children in mass drug administration (MDAs) for trachoma may reduce program impact. Risk factors that identify families where participation is a problem or program characteristics that foster non-participation are poorly understood. We examined risk factors for households with at least one child who did not participate in two MDAs compared to households where all children participated in both MDAs. Read More
Background:
Anti-Wolbachia treatment with doxycycline is effective in sterilising and killing adult Onchocerca volvulus nematodes, proving superior to ivermectin and of great potential as an alternative approach for the treatment and control of onchocerciasis, particularly in areas of Loa loa co-endemicity. Nevertheless, the length of the required treatment poses potential logistical problems and risk of poor compliance, raising a barrier to the use of doxycycline in Mass Drug Administration (MDA) strategies. Read More
WASHINGTON, D.C. (19 March 2012) – In an ambitious effort to stem the dangerous tide of tuberculosis (TB) and deadly drug-resistant TB around the world, TB Alliance today announced that it has launched a first-of-its-kind clinical trial to test a novel drug combination – in both patients who have TB, and those who have multidrug-resistant TB (MDR-TB). Read More
Recent breakthroughs in Chikungunya research spearheaded by scientists at A*STAR’s Singapore Immunology Network (SIgN) have made great strides in the battle against the infectious disease. Working in close collaborations with Singapore clinician-scientists and international researchers , Dr Lisa Ng, Principal Investigator of the Chikungunya research group at SIgN, led the team to discover a direct biomarker which serves as an early and accurate prognosis of patients who have a higher risk of the more severe form of Chikungunya fever (CHIKF). Read More
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New and Emerging Infectious Diseases, An Issue of Medical Clinics, 1e (The Clinics: Internal Medicine) :: Amazon As expanding human communities result in radical modifications to our natural environments, previously harmless micro-organisms take on leth |
The immune system protects from infections by detecting and eliminating invading pathogens. These two strategies form the basis of conventional clinical approaches in the fight against infectious diseases. In the latest issue of the journal Science, Miguel Soares from the Instituto Gulbenkian de Ciência (Portugal) together with Ruslan Medzhitov from Yale University School of Medicine and David Schneider from Stanford University propose that a third strategy needs to be considered: tolerance to infection, whereby the infected host protects itself from infection by reducing tissue damage and other negative effects caused by the pathogen or the immune response against the invader. Read More
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Models for Infectious Human Diseases: Their Structure and Relation to Data (Publications of the Newton Institute) :: Amazon Infectious disease accounts for more death and disability worldwide than either noninfectious disease or injury. This book contains a number |
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Diagnosis and Treatment of Human Mycoses (Infectious Disease) :: Amazon Diagnosis and Treatment of Human Mycoses brings together globally-recognized mycoses experts to guide readers in the use of current knowledg |
Researchers at the University of Dundee have identified fexinidazole as a possible, much-needed, new treatment for the parasitic disease visceral leishmaniasis. Read More
Background:
One of the major complications of Plasmodium falciparum infection is cerebral malaria (CM), which causes one million deaths worldwide each year, results in long-term neurological sequelae and the treatment for which is only partially effective. Statins are recognized to have an immunomodulatory action, attenuate sepsis and have a neuroprotective effect. Atorvastatin (AVA) has shown in vitro anti-malarial activity and has improved the activity of mefloquine (MQ) and quinine. Read More
[Geneva/New York, 1 December 2011] – Less than one-quarter (23%) of children with HIV/AIDS who need treatment are getting it, according to a report released by the World Health Organization (WHO) on the occasion of World AIDS Day (1 December 2011). Read More
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Evaluating HIV/Aids Treatment Programs: Innovative Methods and Findings :: Amazon Create effective community-based programs for substance abusers with HIV/AIDS! Substance abusers are the fastest-growing population of peopl |
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HIV/AIDS Treatment Strategies :: Amazon There are various reasons for taking an interest in the treatment for HIV/AIDS. Unfortunately, AIDS has no cure at the moment. But in the ab |
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HIV Drug Book Revised :: Amazon Project Inform, the nation's leading community-based AIDS treatment information and advocacy organization, presents the first comprehensive, |
Background:
Following the development of resistance to anti-malarial mono-therapies, malaria endemic countries in Africa now use artemisinin-based combination therapy (ACT) as recommended first-line treatment for uncomplicated malaria. Read More
Summary: HIV-positive children are at high risk of drug resistance, which is of particular concern in settings where antiretroviral options are limited. In this Review we explore resistance rates and patterns among children in developing countries in whom antiretroviral treatment has failed. We did a systematic search of online databases and conference abstracts and included studies reporting HIV-1 drug resistance after failure of first-line paediatric regimens in children (<18 years) in resource-poor regions (Latin America, Africa, and Asia).
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Moving Mountains: The Race to Treat Global AIDS :: Amazon An award-winning journalist offers the only global analysis of AIDS treatment and prevention in countries from South Africa to China. In dis |
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Handbook of HIV Medicine :: Amazon The Handbook of HIV Medicine , 2nd edition, is an invaluable practical guide for practitioners at varying levels of expertise who deal with |
Background:
Despite massive anti-malaria campaigns across the subcontinent, effective access to intermittent preventive treatment (IPTp) and insecticide-treated nets (ITNs) among pregnant women remain low in large parts of sub-Saharan Africa. The slow uptake of malaria prevention products appears to reflect lack of knowledge and resistance to behavioural change, as well as poor access to resources, and limited support of programmes by local communities and authorities. Read More
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